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Endometrial differentiation

Schematic illustration showing a proposed model for temporal and spatial distribution of the epithelial and stromal subsets across the menstrual cycle.

The proliferative phase is dominated by a WNT environment that promotes regeneration, while the secretory one showed a compartmentalisation of WNT and NOTCH signaling that promotes efficient differentiation towards the ciliated and secretory lineages.

The uterine cycle.png
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